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The Characteristics of Risk from Viewpoint of Prescription Drugs in Rehabilitation Patients

Received: 10 August 2021    Accepted: 19 August 2021    Published: 26 August 2021
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Abstract

Purpose: Investigating using medicines in rehabilitation patient to understand risks predicted from the effects of those drugs to promote safe rehabilitation. Subjects & Methods: 1039 patients (age mean 75.6±16.91), 392 males (74.05±17.49) and 647 females (76.54±16.60), who receive PT, OT and ST at four medical institutions. The survey items included age, sex, prescribed medications, presence or absence of medication logbook and medical record. The drugs collected in the questionnaire were classified according to the general table of contents of pharmacotherapy specialized book in Japan. Results: 6477 prescription drugs (62 types) for 1039 patients. About 6.23 drugs were prescribed per patient. In order of appearance, Non-Steroidal Anti-Inflammatory drugs (NSAIDs) (742), Peptic ulcer treatment (740), Antihypertensive drugs (699), Laxatives (451), Antipsychotics, Antidepressants, Mood stabilizers and Psychostimulants (423), Infusions and nutritional products (365), Anti-anxiety drugs and Sleeping pills (282). Conculsion: One-third of the patients who participated in this study are at increased risk of falls due to the effects of the drug. Also, the risk of falls increases as the number of drugs increases. Taking more than 5 medications increases the risk of falls from 1.1 to 2.4. The study found that they were taking an average of 6.23 medications and were at high risk of falling. Importantly, PT, OT & ST are not pharmacological experts. We propose that therapists make efforts to understand how prescribed medications affect patients for rehabilitation safety.

Published in Clinical Medicine Research (Volume 10, Issue 4)
DOI 10.11648/j.cmr.20211004.18
Page(s) 155-158
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Medication, Rehabilitation, Risk Management

References
[1] Nanba, Y., Hirotsu, T., Hidani, A., Tanaka, M., Fujie, R., Inata, N., Matsuura, A., Nakaso, N., Kondo, Y., Matsuura, Y., Itagaki, Y., Nagase, T., & Mizuta, Y. (2019). Rehabilitation Risk Management Strategies in Relation to Prescribed Medications. Rigakuryoho Kagaku, 34 (3), 371-375.
[2] Suzuki, Y., Akishita, M., Arai, H., Teramoto, S., Morimoto, S., & Toba, K. (2006). Multiple consultation and polypharmacy of patients attending geriatric outpatient units university hospitals. Geriatr Gerontol Int., 6, 244-247.
[3] Akio E, Kazuyuki S, Shinichi K, et al. Today’s Drug Therapy in 2021. Tokyo. Nankoudou; 2019. 8-18.
[4] Singh G. (1998). Recent considerations in nonsteroidal anti-inflammatory drug gasrtropathy. Am J Med. 105, 31-38.
[5] Shiokawa, Y., Nobunaga, M., Saito, T., Asaki, S., & Ogawa N. (1991). Epidemiological study of upper gastrointestinal disorders caused by non-steroidal anti-inflammatory drugs. Official Journal of Japan College of Rheumatology. 31, 96-111.
[6] Sakamoto, C., Sugano, K., Ota, S., et al. (2006). Case-control study on the association of upper gastrointestinal bleeding and nonsteroidal anti- inflammatory drugs in Japan. Eur J Clin Pharmacol. 62 (9), 765-772.
[7] Miyake, K., Kusunoki, M., Sinji, Y., et al. (2009). Bisphosphonate increases risk of gastroduodenal ulcer in rheumatoid arthritis patients on long-term nonsteroidal anti-inflammatory drug therapy. J Gastroenterol. 44 (2), 113-120.
[8] Geller, AI., Nopkhun, W., Martinez, MN.., et al. (2012). Polypharmacy and the role of physical medicine and rehabilitation. PM&R. 4, 198-219.
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[10] Japan Council for Quality Health Care (2016). Guidelines for the Pharmacologic Management of Neuropathic Pain Second Edition. The Committee for the Guidelines for the Pharmacologic Management of Neuropathic Pain 2nd Edition of Japan society pain clinicians. Tokyo. Shinko trading Co Ltd. 76-77.
[11] Kitahara, M., Ueno, F., Yoshio, Y., Mitsuo, K., et al. (2021). MANUAL OF THERAPEUTIC AGENTS 2021. Tokyo. IGAKUSHOIN 81-108.
[12] Guidelines for the management of hypertension 2019. (2019). Tokyo. Hypertension Treatment Guideline Development Committee (Japanese society of hypertension). 54.
[13] Field M. (2003). Intestinal ion transport and the pathophysiology of diarrhea. J Clin Invest. 111, 931-943.
[14] Hoffman NB. (1991). Dehydration in the elderly. Geriatrics. 46, 35-38.
[15] Guideline for Renal Rehabilitation. Tokyo. Japanese Society of Renal Rehabilitation. 2018; 11-13.
[16] Matsuo, S. (2009). Collaborators developing the Japanese equation for estimated GFR. Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis. 53, 982-992.
[17] Kojima, T., Akishita, M., Nakamura, T., et al. (2012). Polypharmacy as a risk for fall occurrence in geriatric outpatients. Geriatr Gerontol Int. 12, 761-762.
[18] Woolcott, JC., Richardson, KJ., Patel, B., et al. (2009). Meta-analysis of the impact of 9 medication classes on falls in elderly persons. Arch Intern Med. 169, 1952-1960.
[19] Butt, DA., Mamdani, M., Austin, PC., et al. (2013). The risk of falls on initiation of antihypertensive drugs in the elderly. Osteoporos Int. 24, 2649-2657.
[20] By the American Geriatrics Society 2015 Beers Criteria Update Expert Panel. (2015). American Geriatrics Society 2015 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults. J Am Geriatr Soc. 63, 2227-2246.
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Cite This Article
  • APA Style

    Nanba Yoshifumi, Asonuma Yohei, Nagato Saki, Watanabe Juna, Asano Yuka, et al. (2021). The Characteristics of Risk from Viewpoint of Prescription Drugs in Rehabilitation Patients. Clinical Medicine Research, 10(4), 155-158. https://doi.org/10.11648/j.cmr.20211004.18

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    ACS Style

    Nanba Yoshifumi; Asonuma Yohei; Nagato Saki; Watanabe Juna; Asano Yuka, et al. The Characteristics of Risk from Viewpoint of Prescription Drugs in Rehabilitation Patients. Clin. Med. Res. 2021, 10(4), 155-158. doi: 10.11648/j.cmr.20211004.18

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    AMA Style

    Nanba Yoshifumi, Asonuma Yohei, Nagato Saki, Watanabe Juna, Asano Yuka, et al. The Characteristics of Risk from Viewpoint of Prescription Drugs in Rehabilitation Patients. Clin Med Res. 2021;10(4):155-158. doi: 10.11648/j.cmr.20211004.18

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  • @article{10.11648/j.cmr.20211004.18,
      author = {Nanba Yoshifumi and Asonuma Yohei and Nagato Saki and Watanabe Juna and Asano Yuka and Takata Teruhiko},
      title = {The Characteristics of Risk from Viewpoint of Prescription Drugs in Rehabilitation Patients},
      journal = {Clinical Medicine Research},
      volume = {10},
      number = {4},
      pages = {155-158},
      doi = {10.11648/j.cmr.20211004.18},
      url = {https://doi.org/10.11648/j.cmr.20211004.18},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20211004.18},
      abstract = {Purpose: Investigating using medicines in rehabilitation patient to understand risks predicted from the effects of those drugs to promote safe rehabilitation. Subjects & Methods: 1039 patients (age mean 75.6±16.91), 392 males (74.05±17.49) and 647 females (76.54±16.60), who receive PT, OT and ST at four medical institutions. The survey items included age, sex, prescribed medications, presence or absence of medication logbook and medical record. The drugs collected in the questionnaire were classified according to the general table of contents of pharmacotherapy specialized book in Japan. Results: 6477 prescription drugs (62 types) for 1039 patients. About 6.23 drugs were prescribed per patient. In order of appearance, Non-Steroidal Anti-Inflammatory drugs (NSAIDs) (742), Peptic ulcer treatment (740), Antihypertensive drugs (699), Laxatives (451), Antipsychotics, Antidepressants, Mood stabilizers and Psychostimulants (423), Infusions and nutritional products (365), Anti-anxiety drugs and Sleeping pills (282). Conculsion: One-third of the patients who participated in this study are at increased risk of falls due to the effects of the drug. Also, the risk of falls increases as the number of drugs increases. Taking more than 5 medications increases the risk of falls from 1.1 to 2.4. The study found that they were taking an average of 6.23 medications and were at high risk of falling. Importantly, PT, OT & ST are not pharmacological experts. We propose that therapists make efforts to understand how prescribed medications affect patients for rehabilitation safety.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - The Characteristics of Risk from Viewpoint of Prescription Drugs in Rehabilitation Patients
    AU  - Nanba Yoshifumi
    AU  - Asonuma Yohei
    AU  - Nagato Saki
    AU  - Watanabe Juna
    AU  - Asano Yuka
    AU  - Takata Teruhiko
    Y1  - 2021/08/26
    PY  - 2021
    N1  - https://doi.org/10.11648/j.cmr.20211004.18
    DO  - 10.11648/j.cmr.20211004.18
    T2  - Clinical Medicine Research
    JF  - Clinical Medicine Research
    JO  - Clinical Medicine Research
    SP  - 155
    EP  - 158
    PB  - Science Publishing Group
    SN  - 2326-9057
    UR  - https://doi.org/10.11648/j.cmr.20211004.18
    AB  - Purpose: Investigating using medicines in rehabilitation patient to understand risks predicted from the effects of those drugs to promote safe rehabilitation. Subjects & Methods: 1039 patients (age mean 75.6±16.91), 392 males (74.05±17.49) and 647 females (76.54±16.60), who receive PT, OT and ST at four medical institutions. The survey items included age, sex, prescribed medications, presence or absence of medication logbook and medical record. The drugs collected in the questionnaire were classified according to the general table of contents of pharmacotherapy specialized book in Japan. Results: 6477 prescription drugs (62 types) for 1039 patients. About 6.23 drugs were prescribed per patient. In order of appearance, Non-Steroidal Anti-Inflammatory drugs (NSAIDs) (742), Peptic ulcer treatment (740), Antihypertensive drugs (699), Laxatives (451), Antipsychotics, Antidepressants, Mood stabilizers and Psychostimulants (423), Infusions and nutritional products (365), Anti-anxiety drugs and Sleeping pills (282). Conculsion: One-third of the patients who participated in this study are at increased risk of falls due to the effects of the drug. Also, the risk of falls increases as the number of drugs increases. Taking more than 5 medications increases the risk of falls from 1.1 to 2.4. The study found that they were taking an average of 6.23 medications and were at high risk of falling. Importantly, PT, OT & ST are not pharmacological experts. We propose that therapists make efforts to understand how prescribed medications affect patients for rehabilitation safety.
    VL  - 10
    IS  - 4
    ER  - 

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Author Information
  • Department of Physical Therapy, Faculty of Rehabilitation, Kobe International University, Kobe, Japan

  • Department of Rehabilitation, Seijinkai OOKUBO Hospital, Akashi, Japan

  • Department of Rehabilitation, Seijinkai OOKUBO Hospital, Akashi, Japan

  • Department of Rehabilitation, Seijinkai OOKUBO Hospital, Akashi, Japan

  • Department of Rehabilitation, Seijinkai OOKUBO Hospital, Akashi, Japan

  • Department of Rehabilitation, Seijinkai OOKUBO Hospital, Akashi, Japan

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